Skip to main content

Table 2 Results of association study of common CNVs

From: Copy number gain of pro-inflammatory genes in patients with HBV-related acute-on-chronic liver failure

Chr Regions Type Foreground
(case/control)
Background
(case/control)
Odds ratio (OR) P values Genes included*
chr1 16,894,856–16,929,044 Duplication 33/17 337/363 2.09 1.06E−02  
chr1 16,949,054–16,987,299 48/20 307/340 2.66 1.99E−04 MST1L
chr6 103,854,114–103,868,754 79/106 301/274 1.47 1.39E−02  
chr8 7,665,275–7,836,800 142/108 239/258 1.42 1.49E−02 DEFB104A; PRR23D2; SPAG11A; DEFB103A; DEFB105A; DEFB107A; DEFB4A; DEFB106A
chr8 7,202,021–7,259,767 61/38 262/278 1.70 1.09E−02 ZNF705G
chr8 12,260,380–12,487,426 49/28 323/345 1.87 7.56E−03 FAM86B2; FAM66A
chr9 68,055,004–68,312,791 32/15 231/270 2.49 3.01E−03  
chr11 4,928,581–4,930,605 33/57 351/324 1.87 4.25E−03  
chr16 21,297,471–21,501,135 182/147 81/114 1.74 1.52E−03 NPIPB3
chr20 1,509,580–1,520,451 Deletion 303/331 63/42 1.64 1.33E−02  
chr1 173,063,028–173,064,310 87/120 253/230 1.52 7.92E−03  
chr1 110,034,497–110,047,804 89/121 216/196 1.49 1.11E−02  
chr6 29,979,615–30,012,844 49/86 199/171 2.04 3.45E−04 HCG4B
chr6 29,945,293–29,989,326 43/70 121/110 1.79 8.40E−03 HCP5B
chr7 133,446,174–133,449,737 41/71 327/296 1.91 1.33E−03  
chr10 45,905,767–46,573,925 129/97 254/288 1.51 6.14E−03 SYT15; NPY4R; GPRIN2
chr14 40,697,979–40,727,099 47/28 269/289 1.80 1.27E−02  
  1. *Genes include functional genes and lncRNA genes