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Table 1 The top 10 significant biological processes likely associated with respiratory failure in COVID-19 patients, using genes that were identified based on the proximity of 708 SNPs. The genes for each biological process belong to the list of 144 genes. FDR: false discovery rate

From: Identification of biological correlates associated with respiratory failure in COVID-19

Ranking Gene Ontology FDR Genes
1 Wound healing 1.962E-02 ADAMTS13, CCR9, CXCR6, DMBT1, EPPK1, GATA4, ITGB3, MYH1, MYH2, MYH4, PLEC, PRTN3, SMAD3, TFF1, TFF3, UBASH3A
2 Epithelial structure maintenance 1.962E-02 LDB2, TFF1, TFF2, TFF3
3 Cardiac ventricle development 1.962E-02 CCR9, CXCR6, GATA4, ID2, MYH1, MYH4, PTBP1, SLIT3, SUFU
4 Ventricular septum development 1.962E-02 CCR9, CXCR6, GATA4, ID2, SLIT3, SUFU
5 Cardiac septum development 1.962E-02 CCR9, CXCR6, GATA4, ID2, MYH1, MYH4, SLIT3, SUFU
6 Transdifferentiation 1.962E-02 GATA4, SMAD3
7 Muscle system process 2.106E-02 CCR9, CHRNA1, CXCR6, GATA4, MYH1, MYH2, MYH4, TMOD2, TMOD3
8 Cellular component maintenance 2.518E-02 CCR9, CXCR6, DLGAP1, ERC2, PRTN3, TANC1
9 Embryonic foregut morphogenesis 2.624E-02 GATA4, SMAD3
10 Response to virus 2.783E-02 AZU1, CCR9, CXCR6, DDX1, DMBT1, GATA4, IL12A, TRIM5, TRIM6, TRIM22, TRIM34