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Table 1 The top 10 significant biological processes likely associated with respiratory failure in COVID-19 patients, using genes that were identified based on the proximity of 708 SNPs. The genes for each biological process belong to the list of 144 genes. FDR: false discovery rate

From: Identification of biological correlates associated with respiratory failure in COVID-19

Ranking

Gene Ontology

FDR

Genes

1

Wound healing

1.962E-02

ADAMTS13, CCR9, CXCR6, DMBT1, EPPK1, GATA4, ITGB3, MYH1, MYH2, MYH4, PLEC, PRTN3, SMAD3, TFF1, TFF3, UBASH3A

2

Epithelial structure maintenance

1.962E-02

LDB2, TFF1, TFF2, TFF3

3

Cardiac ventricle development

1.962E-02

CCR9, CXCR6, GATA4, ID2, MYH1, MYH4, PTBP1, SLIT3, SUFU

4

Ventricular septum development

1.962E-02

CCR9, CXCR6, GATA4, ID2, SLIT3, SUFU

5

Cardiac septum development

1.962E-02

CCR9, CXCR6, GATA4, ID2, MYH1, MYH4, SLIT3, SUFU

6

Transdifferentiation

1.962E-02

GATA4, SMAD3

7

Muscle system process

2.106E-02

CCR9, CHRNA1, CXCR6, GATA4, MYH1, MYH2, MYH4, TMOD2, TMOD3

8

Cellular component maintenance

2.518E-02

CCR9, CXCR6, DLGAP1, ERC2, PRTN3, TANC1

9

Embryonic foregut morphogenesis

2.624E-02

GATA4, SMAD3

10

Response to virus

2.783E-02

AZU1, CCR9, CXCR6, DDX1, DMBT1, GATA4, IL12A, TRIM5, TRIM6, TRIM22, TRIM34