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Table 4 Univariate and multivariable analysis of prognostic indicators on overall survival and disease-free survival for the prognostic significance of LRIG1 expression of colorectal cancer patients (N = 102)

From: LRIG1 expression and colorectal cancer prognosis

Parameters Overall survival Disease-free survival
Univariate analysis Multivariable analysis Univariate analysis Multivariable analysis
HR (95% CI) P value HR (95% CI) P value HR (95% CI) P value HR (95% CI) P value
Age (years) 0.698 (0.376–1.271) 0.243 0.689 (0.303–1.515) 0.354 0.830 (0.453–1.518) 0.555 0.981 (0.439–2.231) 0.991
(≥ 57 vs < 57)         
Gender 0.944 (0.525–1.658) 0.953 0.859 (0.409–1.755) 0.667 1.029 (0.574–1.806) 0.962 0.923 (0.433–1.921) 0.819
(Male vs female)         
Location 0.833 (0.454–1.495) 0.534 0.996 (0.449–2.164) 0.982 0.775 (0.421–1.388) 0.389 1.044 (0.477–2.237) 0.946
Rectum versus colon         
Tumor size 0.887 (0.490–1.643) 0.736 1.099 (0.512–2.310) 0.837 0.887 (0.489–1.641) 0.733 1.054 (0.471–2.311) 0.928
(≥ 5 cm vs < 5 cm)         
LN metastasis 1.073 (0.588–1.923) 0.855 0.998 (0.448–2.181) 0.581 1.091 (0.604–1.965) 0.787 0.824 (0.364–1.817) 0.625
Yes versus no         
Vascular invasion 1.694 (0.921–2.932) 0.101 1.171 (0.519–2.629) 0.718 1.566 (0.869–2.782) 0.148 1.289 (0.549–3.068) 0.564
Yes versus no         
LRIG1 expression 1.252 (0.690–2.260) 0.473 1.826 (0.823–4.004) 0.151 1.077 (0.597–1.904) 0.831 1.451 (0.656–.081) 0.271
Positive versus negative