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Table 4 Univariate and multivariable analysis of prognostic indicators on overall survival and disease-free survival for the prognostic significance of LRIG1 expression of colorectal cancer patients (Nā€‰=ā€‰102)

From: LRIG1 expression and colorectal cancer prognosis

Parameters

Overall survival

Disease-free survival

Univariate analysis

Multivariable analysis

Univariate analysis

Multivariable analysis

HR (95% CI)

P value

HR (95% CI)

P value

HR (95% CI)

P value

HR (95% CI)

P value

Age (years)

0.698 (0.376ā€“1.271)

0.243

0.689 (0.303ā€“1.515)

0.354

0.830 (0.453ā€“1.518)

0.555

0.981 (0.439ā€“2.231)

0.991

(ā‰„ā€‰57 vsā€‰<ā€‰57)

Ā Ā Ā Ā Ā Ā Ā Ā 

Gender

0.944 (0.525ā€“1.658)

0.953

0.859 (0.409ā€“1.755)

0.667

1.029 (0.574ā€“1.806)

0.962

0.923 (0.433ā€“1.921)

0.819

(Male vs female)

Ā Ā Ā Ā Ā Ā Ā Ā 

Location

0.833 (0.454ā€“1.495)

0.534

0.996 (0.449ā€“2.164)

0.982

0.775 (0.421ā€“1.388)

0.389

1.044 (0.477ā€“2.237)

0.946

Rectum versus colon

Ā Ā Ā Ā Ā Ā Ā Ā 

Tumor size

0.887 (0.490ā€“1.643)

0.736

1.099 (0.512ā€“2.310)

0.837

0.887 (0.489ā€“1.641)

0.733

1.054 (0.471ā€“2.311)

0.928

(ā‰„ā€‰5Ā cm vsā€‰<ā€‰5Ā cm)

Ā Ā Ā Ā Ā Ā Ā Ā 

LN metastasis

1.073 (0.588ā€“1.923)

0.855

0.998 (0.448ā€“2.181)

0.581

1.091 (0.604ā€“1.965)

0.787

0.824 (0.364ā€“1.817)

0.625

Yes versus no

Ā Ā Ā Ā Ā Ā Ā Ā 

Vascular invasion

1.694 (0.921ā€“2.932)

0.101

1.171 (0.519ā€“2.629)

0.718

1.566 (0.869ā€“2.782)

0.148

1.289 (0.549ā€“3.068)

0.564

Yes versus no

Ā Ā Ā Ā Ā Ā Ā Ā 

LRIG1 expression

1.252 (0.690ā€“2.260)

0.473

1.826 (0.823ā€“4.004)

0.151

1.077 (0.597ā€“1.904)

0.831

1.451 (0.656ā€“.081)

0.271

Positive versus negative

Ā Ā Ā Ā Ā Ā Ā Ā