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Fig. 2 | BMC Medical Genomics

Fig. 2

From: DNA methylation abnormalities of imprinted genes in congenital heart disease: a pilot study

Fig. 2

Altered methylation level of the imprinted genes between ASD and VSD and control groups. a, b Imprinted genes up-regulated by methylation between ASD/VSD and control groups. There were two imprinted genes with increasing methylation including GRB10 and MEST in ASD and VSD groups, compared with the normal group. c, i Imprinted genes up-regulated by methylation between ASD and VSD and control groups. Compared with the normal group, 7 of the 18 imprinted genes in ASD and VSD showed decreasing methylation modification including PEG10, NAP1L5, INPP5F, PLAGL1, NESP, MEG3 and H19. ASD and VSD, atrial and ventricular septal defect. *P < 0.05; **P < 0.01

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