Fig. 5
From: DNA methylation abnormalities of imprinted genes in congenital heart disease: a pilot study
Altered methylation level of the imprinted genes between thoracic vascular malformation and control groups. a Hypermethylation of GRB10 gene between thoracic vascular malformation and control groups. b–f Hypomethylation of PEG10, INPP5F, NESP, MEG3 and KCNQ1OT1 respectively between thoracic vascular malformation and control groups. Compared with the normal group, 5 of the 18 imprinted genes in thoracic vascular malformation showed decreasing methylation modification including PEG10, INPP5F, NESP, MEG3 and KCNQ1OT1.TVM, thoracic vascular malformation. *P < 0.05; **P < 0.01