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Fig. 4 | BMC Medical Genomics

Fig. 4

From: Genetic association between CDKN2B/CDKN2B-AS1 gene polymorphisms with primary glaucoma in a North Indian cohort: an original study and an updated meta-analysis

Fig. 4

Forest plot depicting association between CDKN2B variant (rs1063192) under recessive model (GG vs AA + GA) and POAG. The black horizontal lines correspond to the 95% CI and the position of black small squares to the OR per study. The size of the square is proportional to the relative weight of that study in % to compute the overall OR (black diamond). The width of the diamond represents the 95% CI of the overall OR. This study has revealed statistically significant association between this SNP and POAG. This meta-analysis illustrates protection conferred by GG genotype against glaucoma progression with overall OR = 0.64 (p ≤ 0.0001) with no heterogeneity (I2 = 0%; p = 0.82) under fixed effect model

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