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Table 6 Distribution of haplotypes observed for polymorphisms of the CDKN2B and CDKN2B-AS1 genes in total primary glaucoma cases and controls

From: Genetic association between CDKN2B/CDKN2B-AS1 gene polymorphisms with primary glaucoma in a North Indian cohort: an original study and an updated meta-analysis

Haplotypea

Haplotype frequency

Cases

Controls

p value

OR(95% CI)

Frequency in total glaucoma cases versus controls

TATA

0.37

0.37

0.36

0.677

1.04(0.86–1.25)

CATA

0.28

0.33

0.23

< 0.0001*

1.61(1.31–1.98)

CGCG

0.20

0.20

0.19

0.137

1.18(0.94–1.48)

  1. aOrder of SNPs in CDKN2B and CDKN2B-AS haplotypes: rs3217992 C/T, rs1063192 A/G, rs2157719 T/C, rs4977756 A/G
  2. *indicates significant p value
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BMC Medical Genomics

ISSN: 1755-8794

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