Table 8 Meta-analysis of association between CDKN2B rs1063192 polymorphism and the risk of POAG
Genetic models rs1063192 A > G | Model (Fixed effect/random effect) OR (overall) | 95% CI | p value (overall) | Heterogenity (p value) | I2 (%) | Ʈ | Begg test p value | Egger test p value |
|---|---|---|---|---|---|---|---|---|
Dominant model | Random effect 0.76 | 0.69–0.84 | < 0.0001 | < 0.01 | 65 | 0.0214 | 0.1598 | 0.3837 |
Recessive model | Fixed effect 0.64 | 0.59–0.70 | < 0.0001 | 0.82 | 0 | 0 | 0.8048 | 0.2997 |
Heterozygous model | Fixed effect 0.84 | 0.80–0.88 | < 0.0001 | 0.03 | 43.6 | 0.0091 | 0.383 | 0.348 |