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Table 5 Clinical factors identified using cox regression analysis

From: A predictive model for assessing prognostic risks in gastric cancer patients using gene expression and methylation data

Clinical characteristics

Univariate cox regression

Multivariate cox regression

P value

HR (95%CI)

P value

HR (95%CI)

Gender (male/female)

0.05828

1.468 (0.984–2.19)

0.10378

1.4823 (0.9226–2.3818)

Pathologic_M (M0/M1/–)

0.004448

2.495 (1.3–4.788)

0.06341

2.3737 (0.9529–5.9131)

Pathologic_stage (I/II/III/IV/–)

9.24E−05

1.567 (1.249–1.967)

0.92892

0.9803 (0.6325–1.5193)

Radiation therapy (Yes/No/–)

3.35E−03

0.4701 (0.281–0.7865)

0.62836

0.8449 (0.4271–1.6717)

Age (above/below median (65))

0.01833

1.556 (1.074–2.252)

0.04577

1.5779 (1.0086–2.4685)

Pathologic_N (N0/N1/N2/N3/–)

0.002214

1.284 (1.092–1.509)

0.0364

1.3105 (1.0173–1.6883)

Pathologic_T (T1/T2/T3/T4/–)

0.01075

1.345 (1.07–1.691)

0.01735

1.4999 (1.0741–2.0946)

Targeted molecular therapy (yes/no/–)

0.01009

0.609 (0.4158–0.8919)

0.00279

0.4432 (0.2600–0.7555)

New tumor (yes/no/–)

2.57E−09

2.976 (2.042–4.338)

9.21E−08

3.1742 (2.0777–4.8494)