TERT rs2736100 and TERC rs16847897 genotypes moderate the association between internalizing mental disorders and accelerated telomere length attrition among HIV+ children and adolescents in Uganda

Table 3 Two-way analysis of variance for the interaction of internalizing mental disorders with rs2736100 and with s16847897 on telomere length at 12 months

SNP	Obs	Variable	F	Bonferroni corrected p value (α = 0.025)
Baseline
rs2736100	596	IMDs	15.52	< 0.001
		rs2736100	0.98	0.375
		IMDs * rs2736100	1.15	0.318
rs16847897	597	IMDs	2.53	0.112
		rs16847897	0.37	0.692
		IMDs * rs16847897	1.79	0.168
12 months
rs2736100	511	IMDs	6.03	0.014
		rs2736100	0.44	0.645
		IMDs * rs2736100	4.95	0.007*
rs16847897	515	IMDs	7.25	0.007
		rs16847897	3.00	0.050
		IMDs * rs16847897	4.44	0.012*

SNP: single nucleotide polymorphism; Obs: number of observations; IMDs * rs2736100: interaction of internalizing mental disorders with TERT rs2736100 on relative telomere length; IMDs * TERC rs16847897, interaction of internalizing mental disorders with rs16847897 on relative telomere length; *significant p value for the interaction term

ISSN: 1755-8794