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Table 1 Characteristics of the study participants

From: Novel susceptibility loci identified in a genome-wide association study of type 2 diabetes complications in population of Latvia

 

Neuropathies

Nephropathies

Ophthalmic complications

Macrovascular complications

Cases (n = 218)

Controls (n = 382)

P value

Cases (n = 517)

Controls (n = 84)

P value

Cases (n = 203)

Controls (n = 398)

P value

Cases (n = 333)

Controls (n = 226)

P-value

Mean age, years ± SD

55.28 ± 10.24

57.72 ± 10.13

4.61E−03

56.59 ± 10.25

58.57 ± 10.02

1.02E−01

54.38 ± 10.65

58.10 ± 9.80

6.59E−05

56.36 ± 9.88

56.52 ± 10.63

7.58E−01

Female/male, n (%)

120/98 (55.05/44.95)

239/143 (62.57/37.43)

7.85E−02

312/205 (60.35/39.65)

47/37 (55.92/44.05)

5.08E−01

114/89 (56.16/43.84)

245/153 (61.56/38.44)

2.21E−01

190/142 (57.23/42.77)

149/77(65.93/34.07)

4.80E−02

Mean BMI, kg/m2 ± SD

33.27 ± 6.29

33.09 ± 5.96

7.39E−01

33.37 ± 6.00

32.21 ± 6.50

5.18E−02

33.23 ± 6.22

33.2 ± 6.02

8.11E−01

33.46 ± 6.13

32.79 ± 5.97

2.41E−01

Median HbA1c, % (IQR)

7.20 (1.70)

6.90 (1.39)

3.93E−05

7.10 (1.54)

7.00 (1.83)

4.15E−01

7.30 (1.95)

6.91 (1.35)

1.55E−05

7.10(1.85)

6.90(1.15)

3.08E−05

Diabetes duration, years ± SD

6.72 ± 6.09

6.30 ± 4.50

4.07E−01

7.05 ± 6.32

4.79 ± 5.31

3.29E−05

5.95 ± 5.53

6.29 ± 4.45

1.21E−02

5.40 ± 6.09

5.74 ± 4.97

5.88E-03

  1. SD standard deviation, BMI body mass index, HbA1c hemoglobin A1C, IQR interquartile range