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Table 1 Patient-only associations of IL-11 SNPs with HSCR Enteritis stratification

From: Correlation analysis of IL-11 polymorphisms and Hirschsprung disease subtype susceptibility in Southern Chinese Children

SNP A1/A2 E_before operation_SHCSR E_before operation_LHCSR E_before operation_TCA
F_A F_U P OR F_A F_U P OR F_A F_U P OR
rs8104023 C/T 0.02 0.01 0.02 4.05 (1.18–13.93) 0 0.03 0.03 NA 0 0 NA NA
rs4252546 T/C 0.26 0.27 0.71 0.94 (0.70–1.28) 0.26 0.23 0.57 1.17 (0.68 ~ 2.02) 0.20 0.17 0.68 1.29 (0.38 ~ 4.30)
   E_after operation_SHCSR E_after operation_LHCSR E_after operation_TCA
rs8104023 C/T 0.02 0.01 0.04 3.34 (1.01–11.04) 0.00 0.03 0.03 NA 0.00 0.00 NA NA
rs4252546 T/C 0.25 0.27 0.49 0.90 (0.66–1.23) 0.22 0.28 0.25 0.73 (0.43–1.25) 0.18 0.31 0.19 0.49 (0.17–1.44)
  1. SNP, Single Nucleotide Polymorphism; A1/A2 indicates the risk-allele and protective allele to disease; F_A/F_U indicates risk-allele frequency of the SNP in cases or controls; SHSCR, short-segment HSCR; L-HSCR, long-segment HSCR; TCA, total colon aganglionosis; The P-value indicates the significance based on allelic association tests; The calculation of odds ratio (OR) is also based on the risk-allele of each SNP