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Fig. 3 | BMC Medical Genomics

Fig. 3

From: DNA hypermethylation associated with upregulated gene expression in prostate cancer demonstrates the diversity of epigenetic regulation

Fig. 3

UPDOWN genes displayed higher methylation fold changes than UPUP genes. However, UPUP genes also demonstrate strong positive association between methylation and gene expression, supporting the additional relevance of the UPUP pattern in gene regulation. One hundred fifty genes from UPUP, UPDOWN, DOWNUP and DOWNDOWDN groups with the highest DNA methylation fold changes were selected, their gene expression and average DNA methylation fold changes visualized, where each data point represents one gene. Average methylation fold changes were calculated from all corresponding probes in Absher, Kirby and TCGA datasets

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BMC Medical Genomics

ISSN: 1755-8794

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