Table 2 Fractions of all hypermethylated and non-differentially methylated probes in the TCGA DNA methylation dataset for UPUP-only and UPDOWN-only regulation pattern groups, where probes are located in different genomic regions: 3’UTR, 5’UTR, coding exons, exons and introns of the associated genes. Furthermore, fractions of probes that are specifically located in the first coding exon, first exon and first intron is also shown

Part of all hypermethylated probes located in a specific region

Part of all non-differentially methylated probes located in a specific

Part of all hypermethylated probes located in a specific region

Part of all non-differentially methylated probes located in a specific

3’UTR

9.66% (94 probes)

8.53% (36 probes)

7.02% (131 probes)

11.61% (88 probes)

5’UTR

14.25% (130 probes)

13.92% (55 probes

16.14% (297 probes)

13.72% (104 probes)

Coding exons

18.41% (181 probes)

17.26% (73 probes)

14.16% (266 probes)

14.19% (108 probes)

Exons

39.25% (389 probes)

36.49% (158 probes)

35.36% (664 probes)

35.09% (267 probes)

Introns

26.80% (194 probes)

24.57% (86 probes)

26.91% (465 probes)

32.47% (225 probes)

Part of all hypermethylated probes in any coding exon/exon/intron

Part of all non-differentially methylated probes in any coding exon/exon/intron

Part of all hypermethylated probes in any coding exon/exon/intron

Part of all non-differentially methylated probes in any coding exon/exon/intron

First coding exon

64% (116 probes)

72.60% (53 probes)

63.53% (169 probes)

55.55% (60 probes)

First exon

66.84% (260 probes)

61.39% (97 probes)

70.03% (465 probes)

55.06% (147 probes)

First intron

70.62% (137 probes)

69.77% (60 probes)

79.14% (368 probes)

63.11% (142 probes)