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Table 3 Number of hyper-/hypo- methylated promoter in each cancer

From: Impact of mutations in DNA methylation modification genes on genome-wide methylation landscapes and downstream gene activations in pan-cancer

Cancer

Hypermethylated promoter

Hypormethylated promoter

log2 odd ratio

p-value

 

0.05

0.075

0.1

0.05

0.075

0.1

0.05

0.075

0.1

0.05

0.075

0.1

COAD

2,923

921

246

348

41

3

3.0702

4.4895

6.3575

0

1.15E-201

1.E-67

UCEC

2,886

1,329

565

1,343

441

129

1.1036

1.5914

2.1308

1.20E-89

4.52E-88

5.E-62

KIRC

1,747

458

100

1,235

226

38

0.5003

1.0190

1.3959

2.52E-16

5.03E-18

1.E-07

LAML

407

73

15

3,274

1,285

446

-3.0079

-4.1377

-4.8940

0

5.86E-258

2.E-107

LUSC

297

27

1

3,882

886

94

-3.7082

-5.0362

-6.5545

0

2.33E-208

4.E-27

HNSC

63

2

0

2,500

284

15

-5.3104

-7.1497

-infinity

0

1.95E-80

6.E-05

BRCA

310

18

1

1,496

201

27

-2.2707

-3.4811

-4.7548

3.10E-159

8.28E-40

2.E-07

BLCA

87

3

0

1,031

60

3

-3.5668

-4.3219

-infinity

1.21E-187

8.09E-15

2.E-01

LUAD

183

8

2

521

17

0

-1.5094

-1.0874

+infinity

3.97E-36

0.107299

5.E-01