An integrated analysis of public genomic data unveils a possible functional mechanism of psoriasis risk via a long-range ERRFI1 enhancer

Table 3 Candidate functional variants in enhancers associated with psoriasis risk

Chr.	Position	Variant	Alleles (P/R)	RAF	Gene	TF	Marker (P-value, Study)	r²
1	8,257,959	rs72635708	T/C	0.2286	ERRFI1	ARNT, BACH1, FOS, MAFK, NFE2	rs417065 (8.00E-07, [27])	0.9832
11	64,140,624	rs11231770	A/G	0.6292	PPP1R14B	SP1, SP2, ZNF263	rs645078 (2.00E-06, [25])	1.0000

P/R protective/risk, RAF risk allele frequency, NR not reported, TF transcription factor, r² r-squared value between functional variants and GWAS variants