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Table 3 Top differentially methylated regions (DMRs) identified between CD individuals and non-affected controls (|Δβ| > 5%, p < 0.05)

From: Comparison of DNA methylation profiles from saliva in Coeliac disease and non-coeliac disease individuals

hg19 CoordinatesNo. of ProbesAssociated GeneΔβ
Hypomethylated
 chr6:33053576–33,054,0015HLA-DPB1−0.08
 chr2:113190072–113,190,1972RGPD8−0.07
 chr2:130794753–130,795,6784FAR2P1−0.06
 chr20:623089–623,4214SRXN1−0.06
 chr7:100343083–100,343,1102ZAN−0.05
 chr6:31275148–31,276,79724HLA-B−0.05
 chr15:29034942–29,034,9502PDCD6IPP2−0.05
Hypermethylated
 chr1:246667857–246,668,6012SMYD30.13
 chr17:6557720–6,558,8156MIR4520–20.09
 chr15:41098188–41,100,30814ZFYVE190.07
 chr6:32632694–32,633,1638HLA-DQB10.06
 chr6:25882328–25,882,5905SLC17A30.05
 chr11:288301–288,3052ATHL10.05
 chr5:77146796–77,147,1413TBCA0.05
 chr14:24779400–24,780,92614LTB4R20.05