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Fig. 3 | BMC Medical Genomics

Fig. 3

From: Error-corrected sequencing strategies enable comprehensive detection of leukemic mutations relevant for diagnosis and minimal residual disease monitoring

Fig. 3

Development of a specific and sensitive NGS panel for FLT3-ITD detection and disease monitoring. a Serial dilution results for MV4–11 cell line (30 bp ITD in FLT3). The x-axis is allele fraction and y-axis is the number of ITD supporting reads / 10 M sequencing reads. b Nine leukemia samples were analyzed with varying ITD sizes (right y-axis, grey bars) and allele fraction (left y-axis, blue bars). Subjects are across the x-axis, with D = diagnosis, EOI = end of induction, and R = relapse sample

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BMC Medical Genomics

ISSN: 1755-8794

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