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Fig. 3 | BMC Medical Genomics

Fig. 3

From: An integrative, genomic, transcriptomic and network-assisted study to identify genes associated with human cleft lip with or without cleft palate

Fig. 3

Subnetworks of module genes identified by EW_dmGWAS. (A) The top 1 network module from the data in European ancestry. Each circle represents a gene. For the genes with p-value ≥0.05 (insignificant), the color of the circle is set to white. For genes with p-value < 0.05, the area and color of the circle is proportional to gene’s weight. The stronger the color (red) is, the smaller the p-value is, and the stronger weight the gene is assigned. (B) A merged subnetwork of top 10 network modules from the data in European ancestry. (C) A Venn diagram showing the intersection of the 253 genes for European ancestry with the two gene sets in the CleftGeneDB database. (D) The top 1 module from the data in Asian ancestry. (E) A merged subnetwork of top 10 modules from the data in Asian ancestry. (F) A Venn diagram showing the intersection of the 245 genes for Asian ancestry with the two gene sets in CleftGeneDB database

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BMC Medical Genomics

ISSN: 1755-8794

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