Table 3 Pathways enriched in the EW_dmGWAS module genes (Asian dataset)
Pathway ID | Pathway name | Pathway size* | # informative genes$ | Adjusted p-value# |
|---|---|---|---|---|
GO Biological Process | ||||
 GO:2001233 | Regulation of apoptotic signaling pathway | 385 | 26 | 1.9 × 10−7 |
 GO:0043062 | Extracellular structure organization | 400 | 23 | 6.0 × 10−5 |
 GO:0043254 | Regulation of protein complex assembly | 447 | 24 | 1.1 × 10−4 |
 GO:0007409 | Axonogenesis | 449 | 24 | 1.2 × 10−4 |
 GO:1901653 | Cellular response to peptide | 358 | 21 | 2.0 × 10−4 |
 GO:0031589 | Cell-substrate adhesion | 332 | 20 | 2.7 × 10−4 |
 GO:0060627 | Regulation of vesicle-mediated transport | 499 | 24 | 8.5 × 10−4 |
 GO:0002237 | Response to molecule of bacterial origin | 330 | 19 | 1.2 × 10−3 |
 GO:0050730 | Regulation of peptidyl-tyrosine phosphorylation | 244 | 16 | 2.1 × 10−3 |
 GO:0002521 | Leukocyte differentiation | 496 | 23 | 3.0 × 10−3 |
 GO:0034330 | Cell junction organization | 285 | 17 | 3.3 × 10−3 |
 GO:0006914 | Autophagy | 473 | 22 | 5.1 × 10−3 |
 GO:0051123 | RNA polymerase II preinitiation complex assembly | 25 | 6 | 6.1 × 10−3 |
 GO:0038179 | Neurotrophin signaling pathway | 39 | 7 | 6.1 × 10−3 |
 GO:0070482 | Response to oxygen levels | 337 | 18 | 7.7 × 10−3 |
KEGG pathway | ||||
 hsa05203 | Viral carcinogenesis | 201 | 22 | 2.6 × 10−7 |
 hsa05165 | Human papillomavirus infection | 339 | 26 | 1.4 × 10−5 |
 hsa04728 | Dopaminergic synapse | 131 | 12 | 0.014 |
 hsa04215 | Apoptosis | 32 | 6 | 0.023 |