Table 4 GO analysis of network-based feature types
From: Comparative evaluation of network features for the prediction of breast cancer metastasis
Feature Type | Co-expression Network | PPI network | ||||
|---|---|---|---|---|---|---|
| Â | Term | Count | Benjamini corrected p-value | Term | Count | Benjamini corrected p-value |
NO | Growth factor | 24 | 4.10E-02 | G-protein coupled receptor signaling pathway | 49 | 9.40E-01 |
| Â | Jak-stat signaling pathway | 28 | 1.70E-01 | Jak-stat signaling pathway | 19 | 4.30E-01 |
| Â | Cell junction | 49 | 5.90E-01 | Cell junction | 42 | 1.80E-01 |
| Â | Olfactory transduction | 13 | 6.40E-01 | Extracellular region | 111 | 6.60E-02 |
MEAN | RNA transport | 33 | 3.30E-01 | Transmembrane | 479 | 1.60E-24 |
| Â | Lysosome | 40 | 5.00E-01 | Extracellular matrix | 37 | 2.30E-03 |
| Â | Antigen processing and presentation | 19 | 3.60E-01 | Bicellular tight junction | 14 | 8.80E-01 |
| Â | Endothelial cell chemotaxis | 5 | 9.90E-01 | Notch signaling pathway | 6 | 9.2E-1 |
| Â | Â | Â | Â | Leukocyte transendothelial migration | 10 | 9.7E-01 |
MAXIMUM | Cell cycle | 132 | 2.40E-12 | Cell cycle | 122 | 2.70E-10 |
| Â | Antigen processing and presentation | 27 | 7.70E-03 | Positive regulation of canonical Wnt signaling pathway | 36 | 1.60E-05 |
| Â | DNA repair | 45 | 5.20E-02 | T-Cell receptor signaling pathway | 51 | 1.20E-09 |
| Â | Cardiac epithelial to mesenchymal transition | 5 | 9.9E-01 | Cell-cell adherens junction | 70 | 3.50E-05 |
| Â | Â | Â | Â | Positive regulation of blood vessel endothelial cell migration | 7 | 5.7E-01 |
MINIMUM | Cell cycle | 116 | 2.00E-06 | Cell cycle | 136 | 5.90E-14 |
| Â | p53 signaling pathway | 5 | 9.00E-01 | p53 signaling pathway | 19 | 4.90E-02 |
| Â | Rho cell motility signaling pathway | 7 | 9.60E-01 | DNA repair | 41 | 2.80E-01 |
MEDIAN | Cell cycle | 124 | 2.80E-09 | Sensory transduction | 26 | 9.90E-01 |
| Â | DNA repair | 47 | 1.70E-02 | Telomere | 4 | 9.80E-01 |
| Â | CSonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle | 3 | 9.90E-01 | Ribosome | 17 | 9.80E-01 |
VARIANCE | Cell cycle | 138 | 6.30E-18 | Intracellular steroid hormone receptor signaling pathway | 7 | 9.40E-01 |
| Â | DNA repair | 47 | 8.80E-04 | Extracellular space | 177 | 2.10E-01 |
| Â | Positive regulation of telomere maintainance | 12 | 8.00E-02 | Immune response | 64 | 9.50E-01 |
EDGE | Cell cycle | 147 | 1.80E-22 | Cell cycle | 167 | 4.80E-30 |
| Â | Positive regulation of telomere maintainance | 15 | 1.30E-03 | Cell-cell adherens junction | 84 | 5.00E-10 |
| Â | DNA repair | 44 | 7.20E-03 | Positive regulation of epithelial to mesenchymal transition | 7 | 9.5E-01 |
| Â | Cell-cell adhesion | 48 | 1.30E-01 | Regulation of cell motility | 6 | 9.8E-01 |