Table 4 Currently available drugs and drug targets for pancreatic cancer comparing associated target ranks from SCNrank algorithm
Targets | Drug | Targets and their ranks |
|---|---|---|
tyrosine kinase | ||
 EGFR | Erlotinib+Gemcitabine | NA |
 HER2 | Trastuzumab | ERBB2 (14) |
 MAPK | trametinib | MAP2K1 (233) |
 MTOR | everolimus | MTOR (32) |
 IGF-IR | Ganitumab | IGF2R (87) |
 JAK | Ruxolitinib | NA |
Angiogenesis | ||
 VEGF | Bevacizumab | PGK1 (1) |
Others | ||
 KRAS | Gemcitabine+nab-paclitaxel | NA |
 DNA repair | Niraparib | NA |
 Tumor Vaccine | GVAX | NA |