Table 1 Summary of the Most Significant Genes in the GAIN Schizophrenia Data Analysis

FAM69A

1.20 ×10⁻⁵

4.00 ×10⁻⁵

1.70 ×10⁻⁵

6.31 ×10⁻⁶

6.41 ×10⁻⁶

SCZ [33]

Protein binding.

MS [39]

Parkinson’s Disease [29]

NUDT12

6.00 ×10⁻⁵

5.99 ×10⁻³

4.80 ×10⁻⁵

4.29 ×10⁻³

6.58 ×10⁻³

Depressive Symptoms [43]

Regulates the concentrations of individual

nucleotides and of nucleotide ratios.

RPL5

6.00 ×10⁻⁵

9.00 ×10⁻⁵

1.00 ×10⁻⁴

3.57 ×10⁻⁵

2.76 ×10⁻⁵

MS [39]

Ribosomal protein, binds 5s RNA.

HPGDS

8.00 ×10⁻⁵

6.00 ×10⁻⁴

1.50 ×10⁻⁴

5.16 ×10⁻⁵

7.89 ×10⁻⁵

SCZ [34]

PGH2 to PGD2 conversion enzyme.

SMARCAD1

1.00 ×10⁻⁴

1.30 ×10⁻⁴

1.10 ×10⁻⁴

6.06 ×10⁻⁵

1.53 ×10⁻⁴

Heterochromatin organization restoration

epigenetic pattern propagation.

GTF2A1

1.20 ×10⁻⁴

1.00 ×10⁻³

1.70 ×10⁻⁴

9.90 ×10⁻⁵

9.98 ×10⁻⁵

BD [35]

Transcriptional activation.

NRN1L

1.20 ×10⁻⁴

3.50 ×10⁻⁴

6.00 ×10⁻⁴

2.04 ×10⁻⁴

2.63 ×10⁻⁴

Psychiatric Diseases[44]

Neurite growth, neuronal survival.

CERCAM

1.40 ×10⁻⁴

6.00 ×10⁻⁴

1.30 ×10⁻⁴

1.72 ×10⁻¹

1.80 ×10⁻¹

Probable cell adhesion protein.

SLC35A5

1.80 ×10⁻⁴

5.99 ×10⁻³

2.30 ×10⁻³

4.16 ×10⁻⁴

3.32 ×10⁻⁴

Autistic Disorder[30]

Nucleoside-sugar transporter.

STRA13

2.00 ×10⁻⁴

9.00 ×10⁻⁵

9.00 ×10⁻⁵

9.81 ×10⁻⁵

1.07 ×10⁻⁴

SCZ [46]

Mitotic progression and chromosome segregation.

ESRP2

2.90 ×10⁻⁴

2.60 ×10⁻⁴

4.30 ×10⁻⁴

1.85 ×10⁻⁴

1.97 ×10⁻⁴

An epithelial cell-type-specific splicing regulator.

LCAT

6.00 ×10⁻⁴

6.00 ×10⁻⁴

3.10 ×10⁻⁴

9.80 ×10⁻⁴

1.08 ×10⁻³

Enzyme in the extracellular metabolism.

KIAA1024L

1.00 ×10⁻³

6.00 ×10⁻⁴

1.00 ×10⁻³

8.76 ×10⁻⁴

6.66 ×10⁻⁴