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Fig. 4 | BMC Medical Genomics

Fig. 4

From: Highly robust model of transcription regulator activity predicts breast cancer overall survival

Fig. 4

Validation of the transcriptional regulator model with GEO datasets. Kaplan-Meier estimates of the survival of independent breast cancer datasets using the regulator activity signature. a Kaplan-Meier curves of overall survival for a GSE25066, b GSE2034, c GSE3494, d GSE20685, e GSE21653 and f GSE86166. The low-risk and high-risk groups of patients was determined on the basis of the median risk score for each validation dataset. The tick marks on the Kaplan-Meier curves represent censored subjects. The statistically significant differences between the two curves were determined by the two-sided log-rank test. The vertical red dashed line indicates the 10-year mark that was used for interpreting survival difference between groups

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