Fig. 4

Discriminative value and prognostic value of the top 10 directly-related-to-cancer lncRNAs identified by the Cox-filter method for the esophageal cancer application. a Heat-map. b Kaplan-Meier curves. Based on the risk scores calculated using a multivariate Cox regression model, the samples were divided into a high- and low-risk of death groups. From these two plots, it was observed that while the lncRNAs possessed little information for segmentation of EAC and ESCC, they can distinguish the high- and low-risk groups perfectly well. In the Kaplan-Meier plot the log-rank p-value was also given. EAC: esophageal adenocarcinoma; ESCC: esophageal squamous cell carcinoma; LR: low-risk group; HR: high-risk group