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Table 4 KEGG analysis of common genes of brain differentially expressed genes, imprinted genes and autism-related genes

From: Potential role of genomic imprinted genes and brain developmental related genes in autism

ID

Description

GeneRatio

BgRatio

P-value

P-adjust

qvalue

Gene symbol

Has05033

Nicotine addiction

3/8

40/7376

8.12E-0.6

0.000122

5.98E-0.5

GABRA5/GABRG3/GABRB3

Has04727

GABAergic synapse

3/8

88/7376

8.80E-0.5

0.00046

0.000226

GABRA5/GABRG3/GABRB3

Has05032

Morphine addiction

3/8

91/7376

9.73E-0.5

0.00046

0.000226

GABRA5/GABRG3/GABRB3

Has04080

Neuroactive ligand-receptor interactiom

4/8

278/7376

0.000123

0.00046

0.000226

GABRA5/GABRG3/GABRB3/HTR2A

Has04723

Retrograde endocannabinoid signaling

3/8

148/7376

0.000412

0.001235

0.000607

GABRA5/GABRG3/GABRB3

Has04726

Serotonergic synapse

2/8

113/7376

0.006133

0.015332

0.007532

GABRB3/HTR2A

Has00100

Steroid biosynthesis

1/8

19/7376

0.020432

0.043783

0.021508

DHCR7

  1. Id: the number of the path in the kegg database; Description: enriched pathway; GeneRatio: the ratio of the number of genes enriched in the pathway to the total number of genes recognized by the database; BgRatio: the ratio of the number of genes associated with the id to all bg genes; P-value: statistically significant level; Gene symbol: the gene symbol of the gene involved in this pathway