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Fig. 2 | BMC Medical Genomics

Fig. 2

From: Specific chromatin landscapes and transcription factors couple breast cancer subtype with metastatic relapse to lung or brain

Fig. 2

Promoter activation in metastatic cells. a Bar plots of the number of significantly decreased (down) and increased (up) H3K4me3 peaks in the indicated comparison. b Number of significant concordant gene expression changes associated with significant differential promoter activation plotted as in A. c Genome track view of the promoter region of SPARC. d Genome track view of the promoter region of CDH18. All significant peaks defined by p < 0.05, as determined by DESeq2 and BH correction. Genome track heights were scaled within each histone modification, ATAC signal, or RNA pile-up

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