Skip to main content
Fig. 3 | BMC Medical Genomics

Fig. 3

From: Specific chromatin landscapes and transcription factors couple breast cancer subtype with metastatic relapse to lung or brain

Fig. 3

Enhancer activation in metastatic cells. a Bar plots of the number of significantly decreased (down) and increased (up) H3K27ac peaks in the indicated comparison. b Number of significant gene expression changes associated with significant differential linked enhancer activation plotted as in A. c Genome track view of the promoter region of EMP2 and its promoter-enhancer linkages. d Genome track view of the promoter region of RIMS2 and its promoter-enhancer linkages. All significant peaks defined by p < 0.05, as determined by DESeq2 and BH correction. Genome track heights were scaled within each histone modification, ATAC signal, or RNA pile-up

Back to article page