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Fig. 6 | BMC Medical Genomics

Fig. 6

From: Sensitivity to gene dosage and gene expression affects genes with copy number variants observed among neuropsychiatric diseases

Fig. 6

Combined enrichment of dosage-sensitive genes and genes with expression sensitivity only in brain in CNVs observed in five neuropsychiatric diseases in comparison to those in healthy individuals. Human genes were classified into four groups based on the combinations of dosage-sensitive genes and genes with expression sensitivity only in brain: dosage-sensitive genes and genes with expression sensitivity only in brain (DS & ES); dosage-sensitive genes and genes without expression sensitivity only in brain (DS & -ES); dosage-insensitive genes and genes with expression sensitivity only in brain (DinS & ES); and dosage-insensitive genes and genes without expression sensitivity only in brain (DinS & -ES). Asterisks indicate significant enrichment when compared to the healthy individuals in each category

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