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Table 3 HLO-matrix for frequent submodels in the multiplicative model (MAF=0.2) with frequency and power in simulated data

From: Modified entropy-based procedure detects gene-gene-interactions in unconventional genetic models

 

Power

Power

 

HLO-matrix

Freq

\(\widehat {IGmod }_{0}\)

Logistic regression

 

bb

bB

BB

0.07

0.90

1

aa

H

L

L

   

aA

L

H

H

   

AA

L

H

H

   
 

bb

bB

BB

0.36

0.76

0.99

aa

H

L

L

   

aA

L

H

H

   

AA

L

H

O

   
 

bb

bB

BB

0.08

0.53

0.88

aa

H

L

L

   

aA

L

H

H

   

AA

L

O

O

   
 

bb

bB

BB

0.07

0.49

0.91

aa

H

L

L

   

aA

L

H

O

   

AA

L

H

O

   
 

bb

bB

BB

0.07

0.42

0.83

aa

H

L

L

   

aA

L

O

H

   

AA

L

H

O

   
  1. Frequency (freq) of specific submodels and power to detect the interaction for specific submodels. Submodels are described by HLO-matrices as illustrated in Table 1