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Table 4 HLO-matrix for frequent submodels in the epistasis model (MAF=0.1) with frequency and power in simulated data

From: Modified entropy-based procedure detects gene-gene-interactions in unconventional genetic models

 

Power

Power

 

HLO-matrix

Freq

\(\widehat {IGmod }_{0}\)

Logistic regression

 

bb

bB

BB

0.14

0.99

0.98

aa

L

H

H

   

aA

H

L

O

   

AA

H

O

O

   
 

bb

bB

BB

0.22

0.99

0.87

aa

L

H

O

   

aA

H

L

O

   

AA

H

O

O

   
 

bb

bB

BB

0.23

0.96

0.91

aa

L

H

H

   

aA

H

L

O

   

AA

O

O

O

   
 

bb

bB

BB

0.41

0.95

0.65

aa

L

H

O

   

aA

H

L

O

   

AA

O

O

O

   
  1. Frequency (freq) of specific submodels and power to detect the interaction for specific submodels. Submodels are described by HLO-matrices as illustrated in Table 1