Skip to main content
Fig. 3 | BMC Medical Genomics

Fig. 3

From: Absolute measurement of the tissue origins of cell-free DNA in the healthy state and following paracetamol overdose

Fig. 3

The tissue origins of cfDNA in healthy mouse models. a Total amount of cfDNA obtained from a minimum of 10 mice (pooled) per knockout line measured by qPCR of ACTB gene. b Representative cfDNA fragment analysis from hepatocyte-specific knockout mice. Fragments of cfDNA followed mono-, di-, and tri- nucleosome fragment sizes, and large cfDNA fragment size, shown by black arrows c Percentage recombination (1lox%) for each knockout mouse line showing contribution of different cell types to total cfDNA. d A cumulative percentage of cell/tissue contributions to cfDNA from ddPCR

Back to article page

BMC Medical Genomics

ISSN: 1755-8794

Contact us