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Fig. 2 | BMC Medical Genomics

Fig. 2

From: Transcriptome analysis reveals the link between lncRNA-mRNA co-expression network and tumor immune microenvironment and overall survival in head and neck squamous cell carcinoma

Fig. 2

Differentially expressed genes (DEGs) between high and low HNSCC subgroups in male patients. a Venn plot of DEGs. Intersection of datasets contained TIME-associated genes. b Heatmap plot displayed expression differences in DEGs between high and low IS HNSCC patients and normal samples. Transformed read counts of genes using the variance-stabilizing transformation (vst) algorithm were used to represent gene expression in each sample. c Based on GO analysis, up-regulated protein-coding genes in high IS HNSCC subgroup were significantly enriched in immune-related biological processes. Y-axis represents negative logarithm to base 10 of the P-value

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BMC Medical Genomics

ISSN: 1755-8794

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