Fig. 1From: Mitochondrial tRNA methylation in Alzheimer’s disease and progressive supranuclear palsyAssociation results for gene-based GWAS with methylation at site 585. The Q-Q plot (top left) conforms to expectations and shows no sign of genomic inflation. The Manhattan plot (bottom left) illustrates a primary signal in SLC28A3 on chromosome 9 (p-value = 1.935 × 10− 6); as well as multiple suggestive associations on chromosome 15. The regional plot (top right) displays clustering of individual SNPs within an 800 kb window and shows multiple SNPs in LD with the top lead SNP in the gene-based signalBack to article page