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Fig. 2 | BMC Medical Genomics

Fig. 2

From: Mitochondrial tRNA methylation in Alzheimer’s disease and progressive supranuclear palsy

Fig. 2

Association results for gene-based GWAS with methylation across 6 out of 11 sites. The Q-Q plot (top right) conforms to expectations and shows no sign of genomic inflation. The Manhattan plot (bottom left) illustrates a primary signal in TRAIP and IP6K1 on chromosome 3 (8.32 × 10− 7, 6.67 × 10− 7). This result was replicated in 6 out of 11 p9 sites (results for site 12,146 shown here)

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