- Mean ± standard deviation of degree of methylation (inferred from alternative allele frequency) is shown across the top for each site. Non-parametric Kruskal-Wallis p-values with Bonferroni correction (to adjust for multiple comparisons) is shown on the far right. P-values from pair-wise Kruskal-Wallis comparisons between groups are shown within the matrix; p-values< 0.05 (*), p-values< 0.001 (**).