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Table 1 A hypothetical example of the negative data problem

From: An adaptive method of defining negative mutation status for multi-sample comparison using next-generation sequencing

Mutations

Biopsy (#1)

Biopsy (#2)

Read counts (mutant/total)

VAF (%)

Status

Read counts (mutant/total)

VAF (%)

Status #1 (UMC 20X)

Status #2 (MSN)

EGFR (T790M)

40/72

56

Positive

0/15

0

Unknown

Negative

EGFR (C797S)

5/100

5

Positive

0/30

0

Negative

Unknown