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Fig. 1 | BMC Medical Genomics

Fig. 1

From: Gene networks and transcriptional regulators associated with liver cancer development and progression

Fig. 1

Two distinctive subtypes of hepatocellular carcinoma (HCC) were defined by a principal component analysis and b hierarchical cluster analysis. Gene expression values were analysed from 23 HCC samples of various histological grade, as well as 17 surrounding non-tumourous (NT) liver samples. We selected probe sets differentially expressed between 23 HCC samples and 17 NT samples, using a mean absolute ratio ≥ 2 and false discovery rate ≤ 0.05 for the analyses. Based on the results of the analyses, 10 HCC samples with gene expression patterns similar to NT tissues were assigned to the GE1-HCC subgroup, while 13 HCC samples that clearly demonstrated a different gene expression pattern from both GE1-HCC and NT samples were assigned to the GE2-HCC subgroup

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