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Table 4 Fluorescence in situ hybridisation (FISH) analyses of selected chromosomes and histological grade in GE1-HCC and GE2-HCC

From: Gene networks and transcriptional regulators associated with liver cancer development and progression

Samples Mean number of FISH signals per cell* Gene expression HCC subgroup Histological grade (Edmonson)
  CEP1 CEP3 CEP7 CEP8 CEP17
HCC-03-1 1.96 1.60 1.44 1.54 2.05 GE1 1
HCC-09 1.96 2.73 2.29 2 2 GE1 1–2
HCC-02 1.74 1.81 1.75 2.19 1.89 GE1 2
HCC-04 1.85 1.71 1.77 1.87 1.81 GE1 2
HCC-15 1.87 2.36 2.32 1.9 1.89 GE1 2
HCC-16 2.01 2.29 1.99 2.13 1.99 GE1 2
HCC-17 1.76 1.59 1.69 1.68 1.75 GE1 2
HCC-19 1.63 1.86 1.89 1.72 1.64 GE1 2
HCC-05 1.66 1.80 1.61 2.05 1.77 GE1 2–3
HCC-10 2.57 2.33 2.48 1.87 1.92 GE1 2–3
Mean GE1 1.90 2.01 1.92 1.90 1.87   
SD GE1 0.27 0.39 0.34 0.21 0.13   
HCC-03-2 1.86 1.57 1.74 1.76 2.01 GE2 2
HCC-01-1 1.82 1.59 1.69 1.79 1.83 GE2 2–3
HCC-07 4.12 2.87 2.73 2.48 3.4 GE2 2–3
HCC-12 3.88 4.59 3.45 4.44 4.49 GE2 2–3
HCC-13 3.48 2.12 2.63 3.72 4.3 GE2 2–3
HCC-18 3.43 3.39 2.76 GE2 2–3
HCC-20 1.97 3.27 2.34 3.21 2.14 GE2 2–3
HCC-06–2 2.13 2.8 2.58 2.6 2.03 GE2 3
HCC-11 2.09 2.61 2.54 2.48 1.93 GE2 3–4
HCC-14 4.2 4.59 4.55 5.44 4.21 GE2 3–4
Mean GE2 2.84 2.94 2.76 3.07 2.93   
SD GE2 1.05 1.07 0.85 1.17 1.15   
  1. HCC hepatocellular carcinoma, SD standard deviation
  2. *100 cells were counted