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Table 4 Fluorescence in situ hybridisation (FISH) analyses of selected chromosomes and histological grade in GE1-HCC and GE2-HCC

From: Gene networks and transcriptional regulators associated with liver cancer development and progression

Samples

Mean number of FISH signals per cell*

Gene expression HCC subgroup

Histological grade (Edmonson)

 

CEP1

CEP3

CEP7

CEP8

CEP17

HCC-03-1

1.96

1.60

1.44

1.54

2.05

GE1

1

HCC-09

1.96

2.73

2.29

2

2

GE1

1–2

HCC-02

1.74

1.81

1.75

2.19

1.89

GE1

2

HCC-04

1.85

1.71

1.77

1.87

1.81

GE1

2

HCC-15

1.87

2.36

2.32

1.9

1.89

GE1

2

HCC-16

2.01

2.29

1.99

2.13

1.99

GE1

2

HCC-17

1.76

1.59

1.69

1.68

1.75

GE1

2

HCC-19

1.63

1.86

1.89

1.72

1.64

GE1

2

HCC-05

1.66

1.80

1.61

2.05

1.77

GE1

2–3

HCC-10

2.57

2.33

2.48

1.87

1.92

GE1

2–3

Mean GE1

1.90

2.01

1.92

1.90

1.87

  

SD GE1

0.27

0.39

0.34

0.21

0.13

  

HCC-03-2

1.86

1.57

1.74

1.76

2.01

GE2

2

HCC-01-1

1.82

1.59

1.69

1.79

1.83

GE2

2–3

HCC-07

4.12

2.87

2.73

2.48

3.4

GE2

2–3

HCC-12

3.88

4.59

3.45

4.44

4.49

GE2

2–3

HCC-13

3.48

2.12

2.63

3.72

4.3

GE2

2–3

HCC-18

–

3.43

3.39

2.76

–

GE2

2–3

HCC-20

1.97

3.27

2.34

3.21

2.14

GE2

2–3

HCC-06–2

2.13

2.8

2.58

2.6

2.03

GE2

3

HCC-11

2.09

2.61

2.54

2.48

1.93

GE2

3–4

HCC-14

4.2

4.59

4.55

5.44

4.21

GE2

3–4

Mean GE2

2.84

2.94

2.76

3.07

2.93

  

SD GE2

1.05

1.07

0.85

1.17

1.15

  
  1. HCC hepatocellular carcinoma, SD standard deviation
  2. *100 cells were counted
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BMC Medical Genomics

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