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Table 5 Validation of microarray gene expression data by real-time polymerase chain reaction (qPCR) analysis

From: Gene networks and transcriptional regulators associated with liver cancer development and progression

Comparison Gene Microarrays qPCR
Mean FC P Mean FC P
GE1-HCC versus NT MKI67 1.77 0.092 4.92 2.30E-04
HJURP 1.27 0.32 15.84 2.60E-05
KPNA2 1.28 0.253 0.96 0.756
XPOT 1.02 0.949 0.78 0.041
HNF1A-AS1 3.25 0.007 3.19 0.019
H19 0.33 0.006 0.13 0.006
SNAR-A3 1.08 0.813 0.61 0.03
SNAR-B2 0.58 0.305 0.26 0.01
SNAR-H 0.68 0.427 0.92 0.752
GE2-HCC versus NT MKI67 12.96 0 36.64 5.30E-05
HJURP 7.17 0 25.91 1.10E-05
KPNA2 2.63 0 12.81 0.004
XPOT 2.54 0.001 2.26 0.001
HNF1A-AS1 5.27 0 7.05 0.026
H19 4.58 0.002 3.1 0.002
SNAR-A3 7.72 0 24.2 0.002
SNAR-B2 15.83 0 47.5 0.001
SNAR-H 14.05 0 29.55 0.001
GE2-HCC versus GE1-HCC MKI67 7.32 0 7.52 8.40E-05
HJURP 5.63 0 1.68 0.013
KPNA2 2.05 0.001 13.42 0.001
XPOT 2.5 0.003 2.92 1.20E-04
HNF1A-AS1 1.65 0.204 2.21 0.026
H19 14.01 0 23.81 0.002
SNAR-A3 8.33 0 39.58 0.002
SNAR-B2 27.26 0 181.02 0.001
SNAR-H 20.66 0 32.22 0
  1. FC fold change, HCC hepatocellular carcinoma, NT non-tumourous