Fig. 6

Validation of common genes expression in cardiac macrophages from AMI mice and PBMC from AMI patients. a The gene expression changes in cardiac macrophages over the AMI time course, before (day 0) and on days 1, 3 and 7 post AMI, detected by RNA-seq. Seven out of 25 common genes exhibited consistent changes with that in the recruited monocytes/macrophages from infarcted myocardium were shown. *p < 0.05, **p < 0.01 compared with group AMI-d0. b The expression levels of 7 common genes in PBMC from AMI patients at admission measured by microarray. *p < 0.05; **p < 0.01 compared with group post-AMI non-HF; n.s.: no significance. post-AMI non-HF group: n = 8, post-AMI HF group: n = 9. Data are presented as mean ± SEM