Fig. 4
From: MIPP-Seq: ultra-sensitive rapid detection and validation of low-frequency mosaic mutations
Validation of mosaic alleles detected from neural tissues. MIPP-seq validated AAFs from a 432 alleles up to 30%AAF with a subset of alleles b with AAFs below 1%. Correlation of AAFs previously detected by 200X WGS sequencing in brain tissue and MIPP-seq for AAFs less than c 30% and d 10%. Strong correlation of AAFs of WGS and MIPP-seq for both e insertions and f deletions detected and validated in brain derived DNA samples