Table 1 The main laboratory and dexamethasone suppression test results
From: A novel nonsense mutation in ARMC5 causes primary bilateral macronodular adrenocortical hyperplasia
Test | Result | Reference (unit) |
|---|---|---|
WBC | 8.03 | 4–10 (*109/L) |
Hemaglobulin | 128 | 120–160 (g/L) |
Platelet | 141 | 100–300 (*109/L) |
Urinary protein | ± | Negative |
ALT | 21 | 4–41 (U/L) |
AST | 15 | 4–40 (U/L) |
Creatinine | 85 | 59–104 (μmol/L) |
Uric acid | 453.4 ↑ | 202.3–416.5 (μmol/L) |
eGFR | 91 | > 90 (ml/min/1.73 m2) |
HCO3− | 33.3–33.8 ↑ | 22–29 (mmol/L) |
K+ | 2.71–3.73 (low) | 3.50–5.10 (mmol/L) |
FPG | 6.09 | 3.90–6.10 (mmol/L) |
HbA1c | 7.3% ↑ | 4.40–6.50% |
TSH | 0.71 | 0.27–4.20 (μIU/L) |
hsCRP | 2.90 ↑ | 0–1 (mg/L) |
NT-proBNP | 654 ↑ | 83.9 (pg/ml) |
Renin | 0.77 | 0.10–6.56 (ng/ml/hour) |
Aldosterone | 23.75 | 7–30 (ng/dl) |
ARR | 30.84 ↑ | < 25 |
Adrenaline | 1.86 | 1.21–2.30 (nmol/L) |
Noradrenaline | 2.20 | 1.31–2.51 (nmol/L) |
ACTH | 1.63 (low) | 1.60–13.9 (pmol/L) |
Cortisol (8AM) | 332.20 ↑ | 62–194 (μg/L) |
Cortisol (4PM) | 245.20 ↑ | 23–119 (μg/L) |
Cortisol (12MN) | 295.20 ↑ | |
Free cortisol in 24 h urine | 848.24 ↑ | 36–137 (μg/24 h) |
LDDST: cortisol (8AM) | 275.00 ↑ | < 18 (μg/L) |
HDDST: cortisol (8AM) | 239.60 ↑ |