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Table 1 The main laboratory and dexamethasone suppression test results

From: A novel nonsense mutation in ARMC5 causes primary bilateral macronodular adrenocortical hyperplasia

Test Result Reference (unit)
WBC 8.03 4–10 (*109/L)
Hemaglobulin 128 120–160 (g/L)
Platelet 141 100–300 (*109/L)
Urinary protein  ±  Negative
ALT 21 4–41 (U/L)
AST 15 4–40 (U/L)
Creatinine 85 59–104 (μmol/L)
Uric acid 453.4 ↑ 202.3–416.5 (μmol/L)
eGFR 91  > 90 (ml/min/1.73 m2)
HCO3 33.3–33.8 ↑ 22–29 (mmol/L)
K+ 2.71–3.73 (low) 3.50–5.10 (mmol/L)
FPG 6.09 3.90–6.10 (mmol/L)
HbA1c 7.3% ↑ 4.40–6.50%
TSH 0.71 0.27–4.20 (μIU/L)
hsCRP 2.90 ↑ 0–1 (mg/L)
NT-proBNP 654 ↑ 83.9 (pg/ml)
Renin 0.77 0.10–6.56 (ng/ml/hour)
Aldosterone 23.75 7–30 (ng/dl)
ARR 30.84 ↑ < 25
Adrenaline 1.86 1.21–2.30 (nmol/L)
Noradrenaline 2.20 1.31–2.51 (nmol/L)
ACTH 1.63 (low) 1.60–13.9 (pmol/L)
Cortisol (8AM) 332.20 ↑ 62–194 (μg/L)
Cortisol (4PM) 245.20 ↑ 23–119 (μg/L)
Cortisol (12MN) 295.20 ↑  
Free cortisol in 24 h urine 848.24 ↑ 36–137 (μg/24 h)
LDDST: cortisol (8AM) 275.00 ↑ < 18 (μg/L)
HDDST: cortisol (8AM) 239.60 ↑  
  1. WBC white blood cell, ALT alanine aminotransaminase, AST aspertate aminotransferase, eGFR estimated glomerular filtration rate, FPG fasting plasma glucose, HbA1c Hemoglobin A1c, TSH thyroid stimulating hormone, hsCRP hypersensitivity C-reactive protein, NT-proBNP N-terminal prohormone of brain natriuretic peptide, ARR aldosterone renin ratio, ACTH adrenocorticotropic hormone, AM ante meridiem, PM post meridiem, MN midnight, LDDST low-dose dexamethasone suppression test (1 mg overnight), HDDST high-dose dexamethasone suppression test (8 mg/day for 2 days), ↑ the arrow denotes the results above the upper limit of normal