Table 3 Average time and costs for recontact and disclosure

Research genetic variant validation (n = 26)

 Sample preparation

5.5

$22

$123

$5

 DNA retrieval, extraction, aliquoting, and shipping

–

$872

$872

$34

 Laboratory technician

24

$13

$310

$12

 Variant sequencing (reagents, library preparation)

–

$2,325

$2325

$89

 DNA sequencing

–

$694

$694

$27

Subtotal

$4324

$166

Research coordinator (n = 23)

 Study implementation

73.6

$32

$2370

$103

Subtotal

–

–

$2370

$103

Genetic counselor

 Phone calls after letters were sent (n = 23)

4.4

$37.50

$165

$7

 Genetic counseling (n = 11)

8.8

$37.50

$328

$ 30

 Phone calls for CLIA results disclosure (n = 10)

1.5

$37.50

$56

$6

Subtotal

$548

–

Confirmatory genetic testing

 CLIA Laboratory (n = 10)

–

$2500

$2500

$250

Subtotal

$2500

$250

Ancillary costs

 Mailing costs (n = 23)

–

$210

$210

$9

 Research visit room charge (n = 11)

–

$253

$253

$23

 Phlebotomy blood draw (n = 10)

–

$200

$200

$20

Subtotal

$663

–

Project total

$10,405

–

Average cost per participant

–

$400