Fig. 4

The raising allele frequency in HBV related outcomes during the progression. Four SNPs with increased resistance in CHB, ASPI, HBV clearance during HBV infection (a) and two SNPs with increased risk in the CHB, DC, HCC during the development of CHB (b). Abbreviation: ASPI, asymptomatic persistence infection; CHB, chronic hepatitis B; DC, decompensated cirrhosis; HCC, hepatocellular carcinoma