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Table 4 The significance of progressive HBV infection study

From: Genome-wide association study identifies new loci associated with risk of HBV infection and disease progression

SNP Gene P value Resistant Allele Resistant Allele Frequency Related Risk
CHB ASPI Clearance CHB (vs ASPI) Clearance (vs ASPI)
rs615672 HLA-DRB1 1.39 × 10–6 G 0.3297 0.4185 0.5276 0.82 1.12
rs9277542 HLA-DPB1 1.50 × 10–9 T 0.3011 0.375 0.5347 0.84 1.17
rs3128923 HLA-DPA2 2.06 × 10–6 G 0.3804 0.4348 0.5636 0.89 1.14
rs1537862 LACE1 1.85 × 10–6 C 0.6 0.6374 0.7647 0.92 1.19
  1. Abbreviations: ASPI, asymptomatic persistence infection; CHB, chronic hepatitis B. RR was calculated with the comparison of CHB and ASPI, Clearance and ASPI respectively