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Table 2 Top10 pathways and genes in the pathway-gene complex network

From: Identification of major depressive disorder disease-related genes and functional pathways based on system dynamic changes of network connectivity

Pathway

Degree_path

Gene

Degree_gene

Glycerophospholipid metabolism

14

CACNA1A

22

MAPK signaling pathway

11

PTDSS2

19

Hematopoietic cell lineage

10

DIAPH1

15

Regulation of actin cytoskeleton

9

ITGA3

14

Focal adhesion

8

HRAS

14

Neuroactive ligand-receptor interaction

8

MAPK11

11

ABC transporters

8

DUSP8

11

T cell receptor signaling pathway

7

CD19

11

Heparan sulfate biosynthesis

6

PAK6

10

Dilated cardiomyopathy

5

NDST2

10