Identification of major depressive disorder disease-related genes and functional pathways based on system dynamic changes of network connectivity

Table 3 Significant analysis using top 10 genes

Gene	P value_anterior vs control	p_corrected anterior vs prefrontal	P value_prefrontal vs control	p_corrected prefrontal vs control	ROC_anterior	ROC_prefrontal
CACNA1A	0.031	0.062	0.031	0.044	0.606	0.615
PTDSS2	0.003	0.013	0.009	0.030	0.641	0.643
DIAPH1	0.016	0.054	0.008	0.039	0.616	0.644
ITGA3	0.270	0.270	0.072	0.270	0.550	0.600
HRAS	0.032	0.054	0.022	0.054	0.598	0.620
MAPK11	0.256	0.285	0.046	0.051	0.549	0.600
DUSP8	0.086	0.122	0.030	0.050	0.583	0.610
CD19	0.017	0.044	0.035	0.044	0.612	0.608
PAK6	0.128	0.160	0.030	0.060	0.576	0.619
NDST2	0.0007	0.008	0.0009	0.009	0.663	0.680

ISSN: 1755-8794