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Table 4 Drugable target information for the top 10 genes

From: Identification of major depressive disorder disease-related genes and functional pathways based on system dynamic changes of network connectivity

Gene Target (yes/no) Drug counts Drugs PMID
CACNA1A Yes 4 Amlodipine, loperamide, lyrica, pregabalin 25918454, 26390138, 26138193, 26670374
CD19 Yes 1 Blinatumomab
PAK6 Yes 4 Dextromethorphan, Tizanidine, Agmatine, Moxonidine 26471212, 23648652, 26678503, 24333661
MAPK11 Yes 2 KC706, Regorafenib 25563977
PTDSS2 Yes 1 Phosphatidylserine 26689775
DIAPH1 No 0   
ITGA3 No 0   
HRAS No 0   
DUSP8 No 0   
NDST2 No 0