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Table 4 Drugable target information for the top 10 genes

From: Identification of major depressive disorder disease-related genes and functional pathways based on system dynamic changes of network connectivity

Gene

Target (yes/no)

Drug counts

Drugs

PMID

CACNA1A

Yes

4

Amlodipine, loperamide, lyrica, pregabalin

25918454, 26390138, 26138193, 26670374

CD19

Yes

1

Blinatumomab

PAK6

Yes

4

Dextromethorphan, Tizanidine, Agmatine, Moxonidine

26471212, 23648652, 26678503, 24333661

MAPK11

Yes

2

KC706, Regorafenib

25563977

PTDSS2

Yes

1

Phosphatidylserine

26689775

DIAPH1

No

0

  

ITGA3

No

0

  

HRAS

No

0

  

DUSP8

No

0

  

NDST2

No

0