Fig. 9

Identification of ADNP, ANKRD28 and RTN4IP1 in Karpas 422 and SUDHL-4 cells. a qRT-PCR was performed to validate the knockdown efficiency of siADNP, siANKRD28 and siRTN4IP1 in Karpas 422 and SUDHL-4 cells. **p < 0.01; ***p < 0.001. b The effect of ADNP, ANKRD28 or RTN4IP1 knockdown on cell proliferation were detected using CCK-8 method. *p < 0.05, siADNP, siANKRD28 or siRTN4IP1 group vs. siNC group. ^##p < 0.01, siADNP + siANKRD28 + siRTN4IP1 group vs. siADNP, siANKRD28 and siRTN4IP1 group. c The relative mRNA expression levels of ADNP, ANKRD28 and RTN4IP1 in Karpas 422 and SUDHL-4 cells treated with 0, 1 or 2 μM JQ1. *p < 0.05, 1 or 2 μM JQ1 groups vs. control group. **p < 0.01, 1 or 2 μM JQ1 groups vs. control group. d A gene, BMP2, without SE in Karpas 422 and SUDHL-4 cells were screened out. e The relative mRNA expression levels of BMP2 in Karpas 422 and SUDHL-4 cells treated with 0, 1 or 2 μM JQ1